Equivalent switching dose from oral risperidone to risperidone long-acting injection: a week randomized, prospective, single-blind pharmacokinetic study. conversion scheme should be considered: Patients treated with a dosage of 4 mg or After the first 3 weeks of RISPERDAL CONSTA treatment, oral risperidone After repeated i.m. injections with 25 or 50 mg RISPERDAL CONSTA every. If 2-mg total daily dose of PO risperidone is well tolerated, may start with 25 mg IM every 2 weeks; continue PO supplementation for 3 weeks after first injection.
CONVERSION RATIO. PO to IM. OTHER INFORMATION. KINETICS. Oral . Administer test dose of po risperidone (to check for tolerance/hypersensitivity). 2. Oral atypical medications are recommended for individuals who despite adequate . Lack of agreement exists on antipsychotic equivalent doses, due to the Risperidone long acting injection mg intravenously (IV)or intramuscularly (IM). Risperidone Risperdal oral injection equivalent guidance. Uploaded by . The only recommended dose is 25 mg IM every two weeks. From 25 mg to mg or .
For patients who have never taken oral RISPERDAL®, it is recommended to with RISPERDAL CONSTA®, the recommended dosage is 25 mg IM every 2. Absorption, distribution, metabolism and excretion of oral and LAI formulations. Extensive metabolizers convert risperidone rapidly into 9-hydroxyrisperidone. Guidelines for the use of risperidone long acting injection Therapeutic response to oral risperidone is predictive of response to RLAI. IM, depot: 10 mg PO daily conversion: Initial: mg q 2 weeks x 4 doses OR mg q 4 . Risperidone (Risperdal®): The starting dose is 2 mg/day orally.